Recently in this laboratory the viscometric measurement of (4S,6S,12aS)-4-
1,11-dioxo- naphthacene -2-carboxamide[DMPMDC] and (2S, 6R)-7-chloro -2, 4, 6-
trimethoxy-6'-methyl-3H, 4'H-spiro[1-benzofuran 2, 1’-] cychohex-2-ene]-3,4'-
dione[CTMBCD] were carried out at different percentage compositions of solvent to
investigate the solute-solvent interactions of drugs with solvent and the effect of dilution
of the solvent. The effects of various substituents were also investigated. The results
obtained during this investigation gave detail information about pharmokinetics and
pharmodynamics of these drugs.